Synthesis of arylpiperazine substituted bisindolylmethanes as possible pharmacologically active new compounds

Synthesis of Some Nitrogen Functional Derivatives of 5-substituted-6-azauracil as Biologically Active Compounds

3-Arylhydrazono-2,4-dioxo-4-phenylbutanoates have been prepared by the coupling of benzoylpyruvate with aryldiazonium chlorides. Reactions of the 3-arylhydrazono-2,4- dioxo-4-phenylbutanoates with 1-aminoguanidine, semicarbazide, and thiosemicarbazide gave 5-substituted 2-imino-6-azauracil (3a), 6-azauracil (3b), and 2-thio-6-azauracil (3c), respectively. The analytical data of these compounds ...

Synthesis and Studies on Some Pharmacologically Active Sulpha/Substituted Indoles

Some pharmacologically active sulpha/substituted Indoles were synthesised by refluxing the mixture of sulpha/substituted phenyl amine and α-haloacyl benzene in glacial acetic acid. The newly synthesised compounds were characterised by IR, 1H NMR, and UV spectral studies. They were also evaluated for their promising pharmacological activity such as anti-tuberculosis and anti-inflammatory activit...

synthesis of some nitrogen functional derivatives of 5-substituted-6-azauracil as biologically active compounds

Synthesis and Characterization of New 2,5-disubstituted-1,3,4- oxadiazoles as Possible Biological Active Compounds

GABRIELA LAURA ALMAJAN1*, STEFANIA-FELICIA BARBUCEANU1, ILEANA FARCASANU2, CONSTANTIN DRAGHICI3 1 University of Medicine and Pharmacy, Faculty of Pharmacy, Organic Chemistry Department, 6 Traian Vuia Street, 020956 Bucharest, Romania 2 University of Bucharest, Faculty of Chemistry, Organic Chemistry, Biochemistry and Catalysis Department, 90-92 Sos. Panduri, 050663, Bucharest, Romania 3 Romania...

Synthesis of some new tetrahydropyrimidine derivatives as possible antibacterial agents

Heterocyclic compounds containing a pyrimidine nucleus are of special interests due to their applications in medicinal chemistry as they are the basic skeleton of several bioactive compounds such as antifungal, antibacterial, antitumor and antitubercular. As a part of our research in the synthesis of pyrimidine derivatives containing biological activities, some new tetrahydropyrimidine derivati...